Hi Hasan,
My primary experience with packaged nitrogen generators has been in the medium
pressure space (a Parker unit for crystallography) but I would describe that
experience as quite negative. Maybe that unit was a lemon, but the compressors
regularly broke down, the membrane itself ruptured on two occasions (within
the space of four years), and the oxygen sensor failed constantly. You're going
to be dealing with higher pressure and MUCH higher volume but perhaps a sign
not to use Parker as a vendor.
For NMR I currently use boiloff -- still viable over at Genentech although
we had to shut down when Linde had that problem at the Pittsburg plant. At
my previous spots we ran off compressed air with nitrogen separators at POU
(thus pneumatic systems / legs were just using the compressed air).
My recommendation, particularly for a large facility, is as much redundancy
as possible. Probably the systems you have specced out all include dual
compressors but if there is a dryer system involved make sure that it allows
full isolation of the individual towers / units so that you can run during
service or if a valve fails. In all honesty the Zeks dryer towers, although
they do a great job, have given me many more headaches than the compressors
have, mostly due to failures of the switch valve solenoids.
Sparky
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Received on Mon Apr 13 2026 - 15:17:02 MST