AMMRL: Question about J couplings to methyl groups in a chiral molecule

From: Jacobsen, Neil E - (neil) <"Jacobsen,>
Date: Wed, 26 Nov 2014 20:48:55 +0000

I was asked an interesting question by an Organic Chemistry faculty member. In a chiral molecule an ethyl group, CH3-CH2, can have two different chemical shifts for the two geminal protons on the CH2 group. But I've never seen a double-doublet for the methyl group, always a triplet. Why can't the two vicinal J values be different if the two protons on the CH2 are not equivalent? Answers that could be understood by an Organic chemist (including myself in that category) would be much appreciated. Neil Neil E. Jacobsen, Ph.D. NMR Facility Manager Department of Chemistry and Biochemistry University of Arizona 1306 E University Blvd. Tucson, AZ 85721 520-621-8146
Received on Wed Nov 26 2014 - 10:49:39 MST

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