Hallo Clemens,
Am Dienstag, August 08, 2023 18:18 CEST, schrieb "Clemens Anklin via groups.io" <clemens.anklin=bruker.com_at_groups.io>:
> Hi Ken
>
> GdCl3 has in our experience been harder to handle or more precisely get the
> concentration right. It comes in anhydrous form and as hexahydrate and the
> famous GdCl3 * xH2O. This can lead to too much or not enough relaxation.
> Our "doped water" sample contains 0.1 mg/ml of (dry) GDCl3 and this leads
> to a T1 of water in the range of 1 sec. 0.6 mM CuSO4 gives about the same T1.
>
you have to find the correct spot - to get it spot on! Too much - everything
gets broad - too less the relaxation takes too long!
In older days someone came to me with troubles of her Carbon experiment. The
carbons, lonely, are too weak. I told her to get some relaxation reagent into
the sample - Cr(acac)3. She made the first one without the enhancement - and
plotted this out at the AC 250 NMR. Then she repeated it and used too much of
the reagent. So all the CHs went down, but the Carbonyls are getting quite tall.
She also plotted these out. Then she overlayed the two plots and then there
was the spectra she wanted to get. ... good old days with the HP 5770 plotting
device!
Yours sincerely,
Uli
> Best regards
>
> Clemens
>
> On 8/8/2023 11:51 AM, Kenneth Sharp-Knott wrote:
>
> Hi Everyone,
>
> I was hoping to get some insight or tips into water soluble NMR relaxation
> agents. I know that GdCl3 and Copper Sulfate are commonly recommended, but
> I would like some specifics on suggested concentrations and hear about your
> experiences using these.
>
> In my own experience they don't seem to have a general one size fits all
> concentration. There is a fine line between too much and too little GdCl3.
> I'm trying to put together a recommended protocol for students needing a
> water soluble relaxation agent.
>
> Best Regards
>
> --
> Ken Sharp-Knott
> Manager of Analytical Services and the NMR Facility
> Department of Chemistry
> Virginia Tech
>
> (540)267-6502 (Cell)
> (540)231-0885 (Office)
>
>
>
> --
> =========================
==========================
=====================
> Clemens Anklin Ph.D. Vice President
> Bruker BioSpin NMR Applications & Training
> 15 Fortune Drive NEW Phone: 978-313-5NMR(5667)
> Billerica MA 01821 twitter: _at_canklin
> web: http://www.bruker.com
> e-mail: clemens.anklin_at_bruker.com<mailto:clemens.anklin_at_bruker.com>
> =========================
==========================
=====================
>
>
>
>
>
--
=========================
Ulrich Haunz, Dipl.-Ing. (FH)
NMR-Spektroskopie
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Received on Wed Aug 09 2023 - 01:20:58 MST