Hi Joe,
We did 205Tl (and 203Tl) a while ago successfully on our INOVA 500. It
was an ordeal getting it going, but the key part was my having (at that
time) an electronics guy that was able to modify a probe to tune up to
205Tl. It was quite non-optimal in sensitivity, but 205Tl is sensitive
enough that it did (finally) work.
I'm afraid I don't have a probe to offer that could go up to 346MHz. We
do have a variety of older Varian probes still around, but none that
would approach 346 MHz. [If you're willing to pay to have a probe
modified, I'd recommend Jin-Shan Wang at JS Research.]
The main reason I'm writing is to warn you that your INOVA may require
some software adjustments and recabling to get everything to work for
205Tl. What we found on our INOVA was that the X preamp could go up to
205Tl, but the transmitters to get there had to be the 1H/19F set. So
recabling was needed to make that combination work, as well as one
software change. I documented what we had to do at:
http://www.chem.wisc.edu/~cic/nmr/Guides/VUG/Tl205_setup.pdf
Last comment was that I searched around for quite a while before we
finally found 205Tl, which has a large chem shift range. We actually
found the 203Tl resonance first, which then lead to 205Tl. But it took
quite a while, as the probe had to be retuned between different spectral
range searches.
Used absolute referencing (using the proton spectrum) to reference the
205Tl spectrum.
Good luck with this,
Charlie
On 3/2/2015 2:41 PM, Joseph Sachleben wrote:
> Hi AMMRLers,
>
> I have a user who is interested in performing Tl NMR on my 600. I don’t have have a probe that reaches that frequency.
> It would be at 346 MHz, in the gap between 31P and 19F. Would anyone have a retired Varian probe (this spectrometer is
> run by a Unity/INOVA II console with gradients) that could reach that frequency that they would be willing to part with. We
> could negotiate compensation. Another idea I had is to tune down the frequency of the 1H channel on an old inverse 600 MHz
> probe. Does anyone foresee any problems with that idea. I appreciate your time and look forward to hearing your advice.
>
> Joe S.
>
> Joseph R. Sachleben, Ph. D.
> Technical Director Biomolecular NMR Facility
> The Division of Biological Sciences
> 929 E. 57th St.
> Chicago, IL 60637
>
> (773)834-9866
> jsachleben_at_uchicago.edu
>
>
>
>
--
~~~~~~~~~~~~~~~~~~~~~~~
Charles G. Fry, Ph.D. Tel: (608)262-3182
Director, MR Facility Fax: (608)262-0381
Chem. Dept., 1101 University Ave, Univ. Wisconsin-Madison
Madison, WI 53706 USA email: fry_at_chem.wisc.edu
Received on Tue Mar 03 2015 - 09:24:19 MST