AMMRL: PANIC scientific program

From: Amezcua, Carlos <carlos_amezcua_at_baxter.com>
Date: Thu, 20 Sep 2012 16:29:36 +0000

Dear Walt,
Would you mind distributing the Scientific Program for the upcoming PANIC meeting (below) to the AMMRL members?.

Thanks,

Carlos Amezcua on behalf of Joe Ray


Monday, October 15, 2012

07:00 - 17:45 Registration in Mahogany Ballroom Foyer

07:30 - 08:30 Continental Breakfast in Mahogany Ballroom 5, 6 and 7

08:30 - 08:45 CASSS Welcome and Introductory Comments in the Mahogany Ballroom 1, 2, and 3

Edwin Moore, Baxter Healthcare Corporation, Round Lake, IL USA
Darón Freedberg, CBER, FDA, Rockville, MD USA


Quantitation Applications 1

Plenary Session in Mahogany Ballroom 1, 2 and 3

Session Chairs: Kathleen Farley, Pfizer, Inc. and Gonzalo Hernandez, Vis Magnetica


08:45 - 09:10 Yesterday, Today and Tomorrow in NMR

George Gray, Agilent Technologies, Inc., Santa Clara, CA USA

09:10 - 09:35 Quantitative NMR Applications Across a Product Life Cycle

Christina Szabo, Baxter Healthcare Corporation, Round Lake, IL USA

09:35 - 10:00 Universal qNMR: Concentration Referencing without Adding Standards

Huaping Mo, Purdue University, West Lafayette, IN USA

10:00 - 10:15 Discussion - Questions and Answers
10:15 - 10:45 AM Break - Visit the Exhibits and Posters in Mahogany Ballroom 5, 6 and 7


Analysis of Raw Material and Nutritional Supplements

Plenary Session in Mahogany Ballroom 1, 2 and 3

Session Chairs: Carlos Amezcua, Baxter Healthcare Corporation and
Molly Bohlen, Procter & Gamble, Inc.


10:45 - 11:10 Analysis of "Equivalent" Raw Materials Used in Polyurethane Synthesis

James DeFelippis, The Dow Chemical Company, Spring House, PA USA

11:10 - 11:35 Innovative Quantitative NMR for Natural Product Standards and Botanical Standardization

Tanja Gödecke, University of Illinois at Chicago, Chicago, IL USA

11:35 - 12:00 Aloe Vera: Quantification of Key Metabolites for Identity and Quality Assessment
Kim Colson, Bruker BioSpin, Billerica, MA USA

12:00 - 12:15 Discussion - Questions and Answers
12:15 - 13:45 Hosted Lunch


12:45 - 13:45 Technical Luncheon Seminar

New Insights into Quality Control of Food, Beverages and Dietary Supplements by NMR Based Screening

Kimberly L. Colson1,Manfred Spraul2, Birk Schuetz2, Hartmut Schaefer2, Fang Fang2, Eberhard Humpfer2, Jimmy Yuk1, Christian Fischer2

1Bruker BioSpin, Billerica, MA, USA; 2Bruker BioSpin GmbH, Rheinstetten, Germany
Sponsored by Bruker BioSpin Mahogany Ballroom 1, 2 and 3

13:45 - 14:00 Break


Quantitation Applications 2

Plenary Session
Session Chairs: John Edwards, Process NMR Associates, LLC and Kathleen Farley, Pfizer, Inc.


14:00 - 14:25 High Precision Purity Determination by qNMR - How to Achieve an Uncertainty of Measurement of 0.15%?

Torsten Schonberger, Federal Criminal Police Office, Wiesbaden, Germany

14:25 - 14:50 Process Analytical Applications of Quantitative Online NMR Spectroscopy

Michael Maiwald, BAM, Federal Institute for Materials Research and Testing, Berlin, Germany

14:50 - 15:05 Discussion - Questions and Answers
15:05 - 15:35 PM Break - Visit the Exhibits and Posters in Mahogany 5, 6, and 7


15:35 - 16:35 Workshop I: Quantitative NMR: How Good Can We Be, and How

Good Do We Need to Be?

In Mahogany Ballroom 1, 2 and 3
Workshop Chairs: John Marino, NIST and Joseph Ray, Baxter Healthcare Corporation

16:35 -16:45 Mini-Break

16:45 - 17:45 Technical Seminar

Applications of Quantitation in NMR Post-processing

Sergey Golotvin; Patrick Wheeler; Ryan Sasaki

ACD/Labs, Toronto, ON, Canada
Sponsored by ACD/Labs Mahogany Ballroom 1, 2 and 3


17:45 - 19:00 Exhibitor and Poster Reception in Mahogany 5, 6, and 7
19:00 Adjourn Day One


Tuesday, October 16, 2012

07:30 - 17:30 Registration in Mahogany Ballroom Foyer

07:30 - 08:30 Continental Breakfast in Mahogany Ballroom 5, 6 and 7

08:30 - 08:45 Announcements in Mahogany 1, 2 and 3
Joseph Ray, Baxter Healthcare Corporation


Emerging Measurement Science and Technologies

Plenary Session
Session Chairs: Michael Shapiro, Pfizer, Inc. and Edward R. Zartler, Quantum Tessera Consulting


08:45 - 09:10 DOSY NMR - Techniques and Applications

Paul Williard, Brown University, Providence, RI USA

09:10 - 09:35 High-Resolution NMR Spectroscopy on a Chip for Metabolomic Applications

Marcel Utz, University of Southhampton, Southhampton, United Kingdom

09:35 - 10:00 Dissolution Dynamic Nuclear Polarization Studies of Biological Molecules and their Interactions

Christian Hilty, Texas A&M University, College Station, TX USA

10:00 - 10:15 Discussion - Questions and Answers
10:15 - 10:45 AM Break - Visit the Exhibits and Posters in Mahogany Ballroom 5, 6 and 7


10:45 - 11:45 Workshop II: Making the Best Use of Your Data?

in Mahogany Ballroom 1, 2 and 3

Workshop Chairs: Carlos Amezcua, Baxter Healthcare Corporation and
Edward R. Zartler, Quantum Tessera Consulting

11:45 - 13:30 Hosted Lunch

12:15 - 13:15 Technical Luncheon Seminar

The Application of Non-Uniform Sampling (NUS) Techniques to Routine Small Molecule NMR Measurements

Paul J. Bowyer, Agilent Technologies, Inc., Santa Clara, CA, USA

NMR in Big Business: Working in the Intersection of Chemistry, Physics and Time Driven Projects

Don Eldred, Dow Corning, Auburn, MI USA
Sponsored by Agilent Technologies, Inc. Mahogany Ballroom 1, 2 and 3
13:15 - 13:30 Mini-Break


At-Line/In-Line NMR and Time-Domain NMR

Plenary Session in Mahogany Ballroom 1, 2 and 3
Session Chairs: John Edwards, Process NMR Associates and Mark Zell, Pfizer, Inc.


13:30 - 13:55 On-Line Applications of 60 MHz High-Resolution NMR Systems in Industry: Direct Measurements, Chemometric Correlations and Multiple Spectroscopy Data Fusion

John Edwards, Process NMR Associates, Danbury, CT USA

13:55 - 14:20 Online NMR Reaction Monitoring in Pharmaceutical Process Development

David Foley, Pfizer, Inc., Groton, CT USA

14:20 - 14:45 Beyond Hammers in Search of Nails: An Instrument Technologist's Perspective on Developing Miniaturized NMR Spectrometers for New Applications

Andrew McDowell, ABQMR, Inc., Albuquerque, NM USA

14:45 - 15:00 Discussion - Questions and Answers



15:00 - 16:00 Poster Session - Visit Posters in Mahogany 5, 6 and 7



16:00 - 16:25 LF-NMR Studies of Mechanically Induced Gel Syneresis in Cheese

Sřren Engelsen, University of Copenhagen, Frederiksberg, Denmark

16:25 - 16:50 NMR Quantification of Structural Features in Food Science and Technology

John van Duynhoven, Unilever, Vlaardingen, The Netherlands

16:50 - 17:15 Rheological Measurements on Non-Newtonian Fluids Using a Process Compatible MRI

Michael McCarthy, University of California at Davis, Davis, CA USA

17:15 - 17:30 Discussion - Questions and Answers
17:30 Adjourn Day Two


Wednesday, October 17, 2012

07:30 - 13:00 Registration in Mahogany Ballroom Foyer

07:30 - 08:30 Continental Breakfast in Mahogany Ballroom 5, 6 and 7

08:30 - 08:45 Announcements in Mahogany 1, 2 and 3
Joseph Ray, Baxter Healthcare Corporation


Regulatory Topics

Plenary Session in Mahogany Ballroom 1, 2, and 3
Session Chair: John Marino, NIST


08:45 - 09:10 Assessment of the Three-Dimensional Structure of Recombinant Protein Therapeutics at High Resolution Isotopic Enrichment is Not Required

Yves Aubin, Health Canada, Ottawa, ON Canada

09:10 - 09:35 Practical Aspects of Incorporating NMR Based Methods in CMC Strategy of Vaccines

C. Abeygunawardana, Merck & Co., Inc, North Wales, PA USA

09:35 - 10:00 Roles for NMR in Assessing Biosimilars

Darón Freedberg, CBER, FDA, Rockville, MD USA

10:00 - 10:15 Discussion - Questions and Answers



10:15 - 10:45 AM Break - Visit the Exhibits and Posters in Mahogany 5, 6 and 7



10:45 - 11:10 NMR for Assessment of Drug Product Quality: Examples from FDA Studies

David Keire, CDER, FDA, St. Louis, MO USA

11:10 - 11:35 Qualitative and Quantitative Biophysical Comparability Studies on Protein Biopharmaceuticals Using 1D 1H NMR

Julie Wei, Biogen Idec Inc., Cambridge, MA USA

11:35 - 12:00 NMR for the Quantitation of Trace Small Molecules in the Presence of Protein: Applications for Process Development and Process Validation

Ken Skidmore, Genentech, a Member of the Roche Group, South San Francisco, CA USA

12:00 - 12:15 Discussion - Questions and Answers


12:15 - 12:30 Closing Comments - Joseph Ray, Baxter Healthcare Corporation
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Received on Thu Sep 20 2012 - 06:29:43 MST

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