AMMRL: NMR Job Posting at Amgen

From: Silva Elipe, Maria <melipe_at_amgen.com>
Date: Thu, 6 May 2021 17:56:53 +0000

Dear AMMRLers,

We have an NMR position opening in our Thousand Oaks, CA, site at Amgen. We
appreciate any recommendations from our NMR community to fill this position.
The link to apply and a detailed description of the job are below. Please
also contact me at melipe_at_amgen.com<mailto:melipe_at_amgen.com> if you have
candidates of interest.

https://careers.amgen.com/job/12812455/process-development-scientist-technology-thousand-oaks-ca/
Job Description

The Structure Elucidation team within Attribute Sciences provides NMR expertise
for Amgen's clinical and commercial portfolio. Amgen is currently seeking a
Scientist position in our Thousand Oaks facility. The successful candidate will
be primarily responsible for providing NMR expertise in the analysis of synthetic
molecules, which may involve starting materials, intermediates, impurities,
degradation products, and APIs. Additional activities the Scientist may support
include NMR reaction monitoring for chemical process understanding, 3D structural
analysis, and quantitative NMR. The team also provides support for hybrid and
biologic modalities. The Structural Team is also accountable for supporting the
structural elucidation component of regulatory filings.

The Scientist will work closely with a team of analytical and organic chemists
supporting chemical and biological processes by developing NMR methodologies to
understand key aspects of synthetic products, manufacturing, and biologic aspects.
The Scientist will work in collaboration with NMR structural elucidation scientists
across the Amgen network. Our laboratory is equipped with state-of-the art NMR technology.

Key Responsibilities


  * Structural elucidation of small molecules (organics) using state-of-the-at NMR methodologies
  * Support structure characterization of APIs, reference standards, synthetic impurities, and
      degradation products in GLP and GMP environments
  * Collaborate closely with project teams in Process Development
  * NMR analysis of hybrid and biologics modalities
  * qNMR support and training for purity assay
  * Forensic investigations using NMR
  * Lead the elucidation of structure section of CMC regulatory filing for small molecule programs

Basic Qualifications


  * Ph.D. in chemistry or equivalent with at least 2 years of relevant exerience in NMR spectroscopy
      preferable in the pharmaceutical industry
  * Doctorate degree or Doctorate degree completed by June 2021 with mainfocus on NMR
  * Or Master's degree and 4 years of NMR experience
  * Or Bachelor's degree and 6 years of NMR experience

Preferred Qualifications


  * Proven hands-on experience in small-molecule NMR spectroscopy
  * Strong background in organic chemistry and structure elucidation
  * Expertise on NMR methods with proficiency on NMR data systems, pulse sequence language
  * Understanding GLP and GMP requirements
  * Strong written and communication skills
  * Ability to collaborate with project teams in Process Development and work in fast-paced team environment
  * Work well with cross-functional teams, across various geographic locations in different time zones

Thank you and Best Regards,

Maria

Maria Victoria Silva Elipe, Ph.D.
Sr. Principal Scientist | Process Development
+1-805-447-9807 (office)
melipe_at_amgen.com<mailto:melipe_at_amgen.com>

[cid:image013.jpg_at_01D74266.8446F860]
Amgen Thousand Oaks
1 Amgen Center Drive, Thousand Oaks, CA 91320

"I am among those who think that science has great beauty. A scientist in his
laboratory is not only a technician: he is also a child placed before natural
phenomena which impress him like a fairy tale." Marie Curie (1867-1934)

Notice: This communication may contain confidential and privileged information
that is for the sole use of the intended recipient. Any viewing, copying, or
distribution of or reliance on this message by unintended recipient(s) is
prohibited. If you have received this message in error, kindly notify us
immediately by replying to the message and deleting the message and any
attachments thereto from your computer.


Received on Thu May 06 2021 - 07:56:38 MST