NMR based modelling of DNA-protein complexes

From: Mire Zloh <mire.zloh_at_ams1.ulsop.ac.uk>
Date: Wed, 18 May 2005 15:42:03 +0100

Dear all,

we are studying complexes between oligonucleotides and peptide-anthraquinone
conjugates using homonuclear NMR. We are hoping to build NMR based models,
and we are finding difficult to decide which software to use.

Could you please recommend a software for distance constraints generation,
NOE backcalculation and structure calculation that could cope with these
combinations of molecules (DNA, peptides linked to anthraquinone).

Thank you very much.

Best wishes,

Mire

===================================================

Dr Mire Zloh BSc,

Department of Pharmaceutical & Biological Chemistry

The School of Pharmacy

University of London

29/39 Brunswick Square

London

WC1N 1AX

Tel: +44 (0)207 753 5879

Fax: +44 (0)207 753 5964

http://www.ulsop.ac.uk/depts/pharmchem/zloh.html

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Received on Wed May 18 2005 - 18:55:56 MST

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