AMMRL: postdoctoral position open at UCLA

From: Robert Peterson <peterson_at_mbi.ucla.edu>
Date: Wed, 19 Jul 2017 09:47:41 -0700

Dear group,

There is a postdoctoral position open in the lab of Prof. Robert Clubb
here at UCLA. Please feel free to forward the advertisement below to any
interested candidates.

Best regards,

-Robert

-- 
-----------------------------------------------
Robert Peterson, Ph.D.
Facility Manager - NMR Technology Center
UCLA-DOE Institute for Genomics and Proteomics
UCLA Dept. of Chemistry and Biochemistry
phone: (310)825-1816
fax:   (310)825-0982
peterson_at_mbi.ucla.edu
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*Postdoctoral Position at UCLA: Structural Biology of Host-Pathogen 
Interactions*
The University of California, Los Angeles (UCLA), Department of 
Chemistry and Biochemistry, Los Angeles, CA. USA
A postdoctoral position is available in the Clubb laboratory in the 
Department of Chemistry and Biochemistry at UCLA. The Clubb laboratory 
studies how pathogenic bacteria display and utilize virulence factors 
that are required for host colonization. We seek to obtain a mechanistic 
understanding of these processes and to leverage this knowledge to 
discover novel antimicrobial agents. Our research is interdisciplinary 
and employs structural-, chemical-, molecular- and synthetic-biology 
methods.
The postdoctoral scholar will be supported by a NSF grant and will use 
biophysical methods to investigate how the pathogen /Staphylococcus 
aureus/uses the IsdH surface receptor to extract heme from human 
hemoglobin. Studies will reveal the mechanism of extraction for the 
first time and are significant because thisprocess is used by many 
bacterial species to obtain the essential nutrient iron. The 
postdoctoral scholar will perform NMR, stopped-flow spectrometry and 
isothermal titration calorimetry experiments to probe the mechanism of 
heme extraction. He/She will work with our collaborator to 
computationally model this process. Training in x-ray crystallography is 
also available.
Competitive applicants will have a Ph.D. in Chemistry, Biochemistry, or 
a related field. They should have solid training in protein chemistry 
and a demonstrated record of success in developing and/or applying NMR 
methods to study chemical and/or biochemical systems. Ideal candidates 
will have experience in multidimensional NMR and bacterial expression of 
proteins. The project is supported by excellent NMR, crystallography and 
biophysics instrumentation facilities.
Inquiries and applications should be directed by email to Prof. Robert 
Clubb (rclubb_at_mbi.ucla.edu <mailto:rclubb_at_mbi.ucla.edu>; 
http://www.biochemistry.ucla.edu/biochem/Faculty/Clubb). Applications 
should include a CV, brief description of research interests and contact 
information for references.
The University of California is an equal opportunity employer.

Received on Wed Jul 19 2017 - 06:52:35 MST