NMR with 14C or 3H labeled molecules

From: CHAPDELAINE, Guillaume <Guillaume.CHAPDELAINE_at_crit.rhone-poulenc.com>
Date: Mon, 19 Feb 2001 11:35:47 +0100

Dear AMMRL,

I am going to analyze molecules by 1H/13C NMR but these molecules have been partially 14C or 3H labeled.

What is the influence of isotopes on 1H/13C NMR spectrum (coupling constants...)?

Is it possible to observe 3H nucleus by NMR?

What kind of safety requirement may I use to manipulate 14C or 3H labeled molecules (special NMR tubes, probes...)

Thank you for your answers.

_______________________________________________________
Guillaume CHAPDELAINE
RHONE-POULENC INDUSTRIALISATION
CRIT Décines
ANA/STR/RMN
24, Avenue Jean Jaurès
69153 DECINES CHARPIEU Cedex
FRANCE

Tél. : (33) (0)4 72 93 59 70
Fax : (33) (0)4 72 93 54 43
Cour. : guillaume.chapdelaine_at_crit.rhone-poulenc.com
Received on Mon Feb 19 2001 - 09:45:26 MST

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