Hi all,
I have just found that Dr. Istvan Pelczer developed a novel
technique for
processing normal COSY spectrum in 1991 (JACS, 113, 3211-3212). With this
technique, the antiphase diagonal peak can be removed so that cross peaks can
be easily seen even they are close to the diagonal.
As Dr Pelczer described in his paper, the data processing procedure
includes the following major steps:
phasing the diagonal peaks to pure absorption in both dimensions, removal (or, alternatively, scaling)
of the diagonal, replacement of imaginary data using Hilbert transformation, and rephasing
in both dimension by 90 degrees. This processing gives a simplified COSY spectrum (S. COSY).
If you have a FELIX or VARIAN-VNMR macro which performs the above processing and you are
willing to share your macro with me, would you please send me a copy.
Thanks a lot.
Weixing Zhang, Ph.D.
Department of Structural Biology
St. Jude Children's Research Hospital
332 North Lauderdale Street
Memphis, TN 38105
Voice: (901)495-3169
Fax: (901)495-3032
http://www.stjude.org/departments
Received on Tue Aug 15 2000 - 11:19:49 MST