Hello Everyone,
I'd like to announce the second NMR Bootcamp (Practical NMR) at the
National High Field NMR Centre at the University of Alberta August
13th-18th. The seminar will coincide with the Edmonton International
Fringe Festival so there will be an abundance of non NMR activities
as well. Please got to www.nanuc.ca for registration and schedule
information. Speakers will be as follows;
CLEMENS ANKLIN
VICE-PRES. BRUKER
BioSpin - TopSpin
Dr. Clemens Anklin is a Vice President of Applications and Training
for Bruker and an experienced user of the TopSpin software packaged
that operates their spectrometers used to acquire high resolution
multi-dimensional NMR data.
Dr. Clemens received his Ph.D. from the Swiss Federal Institute of
Technology (ETH Zurich) and has been with Bruker since 1988. He
presented at the first NMR BootCamp and also presented last year at
the first "NANUC Roadshow" in London Ontario regarding non-uniform
rapid NMR data acquisition on Bruker Instrumentation. His focus this
year will be the set-up, acquisition and processing of BioNMR
experiments. The lecture will also include a discussion of the latest
additions to the experimental library and new features.
We are very pleased that he will be able to join us again in August
and we look forward to his lively presentation style.
JEFF HOCH, DIRECTOR
NMR STRUCTURAL BIOLOGY FACILITY
UNIVERSITY OF CONNECTICUT HEALTH CENTER, CT, USA
Rowland NMR ToolKit (RNMRTK)
Jeff Hoch is a professor at the University of Connecticut who
specializes in the processing of NMR data. His work specifically
focuses on novel methods of data collection not limited to the use of
Fourier Transformations.
NANUC was fortunate enough to have Prof. Hoch present at last year at
the first offsite training course in London, Ontario, but the 2007
BootCamp will be Prof. Hoch's first BootCamp experience and the first
time he will visit the national NMR centre in Edmonton (he has
graciously agreed to try the straightjacket show at the Fringe
Festival taking Wayne Fairbrother's place).
Prof. Hoch will be presenting the capabilities of the Rowland NMR
ToolKit (commonly known as the RNMRTK) and will be demonstrating to
students how to process rapid acquisition (i.e. non-uniform or non-
linear) NMR data incompatible with traditional processing methods.
We eagerly look forward to his visit and latest developments.
GEORGE GRAY
VARIAN INC. USA
VNMRJ and BioPack
Dr. Gray is a veteran of the Canadian national training courses here
at NANUC and 2007 will be his second BootCamp and third invitation to
NANUC. In 2001 Dr. Gray presented the predecessor to BioPack (then
called ProteinPack which was later combined with RNAPack).
Dr. Gray will cover the newest version of the VNMRJ spectrometer
software. Students will learn how to navigate the new system and
utilize the various new user friendly components as well as perform
customizations of their environments for individual requirements.
The demonstrations will then progress to the BioPack software suite
of multi-nuclear and multi-dimensional pulse sequences. BioPack was
designed to provide "User-friendly" water suppression, double and
triple resonance 2D/3D/4D pulse sequences, including TROSY options
and BioNMR PSG programming; featuring automatic calibration and
experiment execution. It includes experiments for non-labeled and
labeled biomolecules such as peptides, proteins, RNA and DNA's.
Attendees will be able to utilize cutting edge pulse sequences from
large contributing laboratories such as the Lewis Kay (Univ. of
Toronto) Pulse sequence library.
CHARLES D. SCHWIETERS
HEAD, STRUCTURAL BIOLOGY GROUP NIH
XPLOR-NIH
Dr. Schwieters received his B.Sc. from the University of Virginia and
his Ph.D. in Chemistry from Princeton.
He is involved in the planning and implementation of novel algorithms
for probing protein structure and dynamics. He is responsible for the
development and maintenance of the XPLOR-NIH and VMD-XPLOR software
packages. He also supervises a small group at the main NIH campus.
2007 will be Charles' second NMR BootCamp and this year's focus will
be on a more stepby-step approach to solving BioNMR problems with an
emphasis on protein 3D structures and how to easily incorporate data
and evaluate final solutions. Students will be presented with
background information and then given several example problems to
work on. Help will be provided and participants should leave with a
basic understanding and ability to utilize the program to solve their
research goals.
FRANK DELAGLIO
NIH
NMRPipe, NMRDraw, TALOS DYNAMO
Dr. Frank Delaglio is very familiar with the NANUC training courses
having presented at a specialized course in 2003 and our first
BootCamp during 2005. We of course enthusiastically included him in
this years festivities and he has graciously volunteered to arrive
early and stay late to answer students questions (you can also catch
him earlier in the virtual world of "Second Life" as seen top image
above).
Dr. Delaglio (aka the Big F. or the Big D.) will be presenting the
extensive software suite from Prof. Ad Bax's laboratory at the
National Institutes of Health. The software includes the well known
and widely utilized NMRPipe, NMRDraw processing tools as well as the
powerful TALOS, and DYNAMO programs. The emphasis this year will be
on real world examples for students to work through.
As always we look forward to Frank's detailed yet relaxed lecture style.
LEO SPYRACOPOULOS
UNIV. OF ALBERTA
Mathematica Notebooks
Dr. Spyracopoulos is an Associate Professor in the Department of
Biochemistry at the University of Alberta. The Spyracopoulos
laboratory is involved in determining the dynamics, structures, and
interactions of enzymes of the ubiquitination cycle, a biochemical
process important in DNA repair and the immune response.
Dr. Spyracopoulos specializes in the analysis of protein dynamics
through measurement of 15N NMR relaxation. He recently developed a
suite of Mathematica (Wolfram Research) Notebooks for analysis of
protein dynamics data which are available via his laboratories web
site. The key features of the programs include ease of use, automatic
visualization of data and results, and computer compatibility.
The aims of this afternoon workshop will be to familiarize students
with analysis of protein main chain 15N dynamics using methods such
as spectral density mapping and the "model-free" approach. The
applicability of the methods with respect to spectral quality and
sample conditions such as protein oligomerization will be discussed.
Overall, students will learn how to carefully analyze protein main
chain dynamics data, apply dynamics approaches to answer questions
regarding biological function, and use dynamics analyses to
complement protein structure determination.
PASCAL MERCIER
CHENOMX INC. EDMONTON ALBERTA
CYANA
Dr. Pascal Mercier is another veteran of the NANUC workshops. He is a
structural biochemist with a passion for developing mac software and
making programs more user friendly and accessible. He originally got
involved coding additions for the C-version of NMRView called the
"Navigator".
Dr. Mercier received his degree from the Brian Sykes laboratory at
the University of Alberta, and he has recently begun working for
Chenomx Inc., Edmonton, Alberta. He is involved in developing
software capable of automatically interpreting spectra and
identifying metabolic markers from human body fluids.
He originally became interested in CYANA after discovering the speed
that structures could be generated using the different calculation
algorithms incorporated into CYANA. He has since written conversion
scripts with GUIs (graphic user interfaces) in order to facilitate
the incorporation of NMRView data more easily into the structure
calculation program.
We are extremely fortunate to have Dr. Mercier join us for the
afternoon and we are grateful to Chenomx for providing his expertise
to our workshop.
BRUCE JOHNSON
PRESIDENT, ONE MOON SCIENTIFIC
NMRView J
Bruce Johnson is Founder and President of One Moon Scientific, Inc.
He is the creator of NMRView, one of the leading programs for the
analysis and visualization of data on proteins and nucleic acids from
Nuclear Magnetic Resonance spectrometers.
Prior to One Moon Scientific, Inc., Bruce was a Senior Research
Fellow at Merck & Co., Inc. During his 15 year career at Merck he
specialized in applying the methods of structural biology, molecular
modelling, and cheminformatics to research in drug discovery. Bruce
holds a BS degree from the University of Washington and a PhD from
Duke University.
Presentations will include all the operational features of NMRViewJ
(i.e. opening data, making assignments, picking NOEs for structure
calculations, and exporting). Students will gain the ability to
analyse spectra from multi-dimensional experiments and how to proceed
access online resources for further individual progress.
Please contact myself or Dr. Ryan McKay if you require further details.
Deryck Webb
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Deryck Webb - NMR Technologist
NANUC - Canada's National High Field NMR Centre
Room 103 Email: deryck_at_nanuc.ca
NANUC Bldg. Phone: (780) 707-0857
University of Alberta Fax: (780) 492-9174
Edmonton, Alberta Cell: (780) 707-0857
Canada T6G 2E1 AIM: derycknmr
http://www.nanuc.ca
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Ryan T. McKay, Ph.D. - Scientific Director
NANUC - Canada's National High Field NMR Centre
Room 105 Email: ryan_at_nanuc.ca
NANUC Bld. Phone: (780) 492-2700
University of Alberta Fax: (780) 492-9174
Edmonton, Alberta Cell: (780) 920-8871
Canada T6G 2E1 AIM: ryanmckaynmr
http://www.nanuc.ca
Received on Tue Apr 10 2007 - 11:59:54 MST